Draft Scientific Programme

OCTOBER 16, WEDNESDAY, 2019

08:30 – 12:00

REGISTRATION

12:00 – 14:00

LUNCH

13:30-14:00

CEC-1

Use of Biomarkers in Human Biomonitoring

CEC-2


Recent Developments and The Use of Non – invasive Samples in Comet Assay

14:00-14:30

Biomarkers of Exposure and

Early Biological Effects

Stefano Bonassi (Italy)

The Use of the Best Biomarker from the Best (Non-invasive) Tissue

Sabine Langie (Belgium)

14:30-15:00

Study Design in Molecular Epidemiology

Stefano Bonassi (Italy)

The Use of Different Blood Cell Preparations in the Comet Assay

Andrew Collins (Norway)

15:00-15:30

Statistical Analysis of Human Studies with Biomarkers

Stefano Bonassi (Italy)

The Use of Buccal Cells in Human Biomonitoring and Early Disease

Mirta Milic (Crotia)

15:30-16:00

Designing a Biomonitoring Study: Practical Exercise

Stefano Bonassi (Italy)

Confounding Factors Affecting Comet Assay Results in Human Biomonitoring Studies

Amaia AZQUETA ( Spain )

16:00-16:30

A comparison of DNA Damage levels, assessed in placenta Tissue and Umbilical Cord blood (NEOGENE project)

Carla Costa ( Portugal )

17:00-17:15
OPENING CEREMONY
17:15-17:45

OPENING LECTURE


Toxicology from The Perspectives of a Journal Editor

Hermann BOLT (Germany)

17:45-19:00
WELCOME RECEPTION
19:30-21:30

DINNER

OCTOBER 17, THURSDAY, 2019

9:00-9:30

PLENARY LECTURE – Mary GULUMIAN (South Africa)

State of Science of the Risk Assessment of Nanomaterials

9:30-10:00
COFFEE BREAK

SESSION-I
RECENT DATA on CARCINOGENICITY STUDIES

10:00-10:30

Carcinogenicity Studies-Overview of Guidelines

Hanan GHANTOUS (USA)

10:30-11:00

Carcinogenicity Studies and Status of ICHS1 and Implications

Owen McMaster (USA)

11:00-11:30

Carcinogenicity of Immune Modulators

Kenneth HASTINGS (USA)

11:30-12:00

Biomarkers of Cancer Risk

Stefano Bonassi (Italy)

12:00-12:30

DNA Repair in Cancer Therapy

Miral DİZDAROĞLU (USA)

12:30-14:00
LUNCH

SESSION-II


EMERGING ENVIRONMENTAL ISSUES

SESSION-III

USE of COMET ASSAY in BIOMONITORING of DNA DAMAGE in DIFFERENT SETTINGS

14:00-14.30

Immunotoxicity of PFAS as Drinking Water, Food and Occupational Contaminants

Emanuela CORSINI (Italy)

Genomic Damage in Obesity and after Weight Loss

Helga STOPPER (Germany)

14:30-15:00

Human Health Effects of Cyanotoxins

Emanuela TESTAI (Italy)

Plant Comet Assay in Environmental Studies

Bertrand POURRUT (France)

15:00-15:30

Climate Change and Food Safety

Angelo MAGGIORE (Italy)

The Importance of Individual Susceptibility on the Levels of DA Damage: the Case of Styrene-exposed Workers

Joao Paulo TEXEIRA (Portugal)

15:30-16:00

Microplastics: are they really a threat?

Emanuela Testai ( Italy )

The comet assay testing nanomaterials in advanced in vitro models
Maria DUSINSKA (Slovakia)
16:00-16:30
COFFEE BREAK
COFFEE BREAK
17:00-18:45
SHORT PRESENTATIONS-1
SHORT PRESENTATIONS-2

EXHIBITOR-HOSTED WORKSHOP

MatTek In Vitro Reconstructed 3D Models For The Safety Assessment of Chemicals, Cosmetics, Drugs And Medical Devices

18:45-19:15
POSTER PRESENTATIONS

OCTOBER 18, FRIDAY, 2019

9:00-9:30

PLENARY LECTURE – Salmaan H. INAYAT-HUSSAIN (Malaysia)


Human Health Protection Through Chemical Stewardship – An Industry Perspective

9:30-10:00
COFFEE BREAK

SESSION-IV


FOOD SAFETY

SESSION-V


ORGAN SPECIFIC TOXIC REACTIONS and RELATED ADVERSE OUTCOME PATHWAYS

10:00-10:30

The Importance of Risk Communication in Food Safety

Martin Wilks ( Switzerland )

Contribution of Mitochondria to Clozapine-Induced Cardiotoxicity and Paracetamol-Induced Hepatotoxicity

Hilmi ORHAN (Turkey)

10:30-11:00

Practices of Risk Assessment in Food Safety in Turkey

Serap HANCI ( Turkey )

Adverse Outcome Pathways Associated with Mitochondria

Mathieu VINKEN (Belgium)

11:00-11:30
The Reproductive Toxicity of Mycotoxins
Hassan MALEKINEJAD ( Iran )

Adverse Drug Reactions: Molecular Mechanisms and Inter-individual Differences

Nico P.E. Vermeulen (The Netherlands)

11:30-12:00

PFOS and PFOA in food: main conclusions of the EFSA 2018 risk assessment

Tanja SCHWERDTLE ( Germany)

Influence of Epigenetic Mechanisms in Kidney Toxicity: Ochratoxin A and Fumonisins

Sibel ÖZDEN (Turkey)

12:00-12:30

Nutraceuticals: Aspects of Efficacy and Toxicity in the Genomic Era
Marco RACCHI (Italy )

The search for an optimal human liver line for the Detection of Mutagens

Siegfried Knasmueller ( Austria )

12:30-14:00
LUNCH

SESSION-VI


APPLICABILITY and LIMITATION of NON-ANIMAL TESTING in SAFETY ASSESSMENT

SESSION-VII


ENDOCRINE DISRUPTING EFFECTS of CHEMICALS and PHARMACEUTICALS- THEIR ROLE in DISEASES

14:00 – 14.30

Regulatory Use of Non Animal Models: Limitations and Pitfalls

Emanuela TESTAI (Italy)

Nonclinical Evaluation of Endocrine-Related Drug Toxicity: Experiences with novel drug candidates and herbal dietary supplements

Hande GURER-ORHAN (Turkey)

14:30 – 15:30

History of a Success: Contact Hypersensitivity

Emanuela CORSINI (Italy)

FDA CLARITY-BPA (The Consortium Linking Academic and Regulatory Insights on Bisphenol A Toxicity) Study: Safety Assessments and Non-Monotonic Dose Response

Neslihan AYGUN-KOCABAS (Belgium)

15:00 – 15:30

Applicability of Non Animal Testing for Food and Feed Safety Assessment

Jean-Lou DORNE (Italy)

Towards a harmonized integrated assessment of metabolism disrupting compounds (The GOLIATH Project)

Jorke KAMSTRA (The Netherlands)

15:30 – 16:00

The Use of Organ-on-a-chip Technologies in Toxicological Research

Paul VULTO (Netherlands)

Role of Endocrine Disruptors in Various Pathological Conditions: A special focus on Phthalates, Bisphenols and Polychlorinated Biphenyls

Pınar ERKEKOGLU (Turkey)

16:00 – 16:30

Future Perspectives of in Non-animal Models

Thomas HARTUNG (USA)

Adverse Effects of Psychoactive Drugs on Sperm Parameters: The Role of the Hypothalamic-Pituitary-Gonadal Axis

Sinem ILGIN ( Turkey )

16:30 – 17:00
COFFEE BREAK
17:00 – 18:30
SHORT PRESENTATIONS-3

SHORT PRESENTATIONS-4

18:30 – 19:30
POSTER PRESENTATIONS

GALA DINNER

OCTOBER 19, SATURDAY, 2019

9:00-9:30

PLENARY LECTURE – Mohammad ABDOLLAHI (Iran)


LATE EFFECTS of CHRONIC PESTICIDE EXPOSURE in HUMANS

9:30-10:00
COFFEE BREAK

SESSION-VIII


OCCURRENCE, USE and POTENTIAL TOXIC EFFECTS of METALS

SESSION-IX


LIPIDOMICS

10:00 – 10:30

Toxicity of Arsenic Species: Lessons from Cells, Flies , Worms, Mice and Humans

Tanja SCHWERDETLE (Germany)

Impact of Oxysterols on the Peroxisome: Physiopathological consequences

Gerard LIZARD (France)

10:30 – 11:00

Reproductive and Developmental Effects of Boron in Humans Under Occupational and / or Environmental Exposure Conditions

Yalçın DUYDU (Turkey)

Cholesterol and Related Sterol Autoxidation

Luigi IULIANO (Italy)

11:00 – 11:30

Cadmium Impact on Increased Risk of Osteoporosis

Vesna MATOVIĆ (Serbia)

Use of Tandem Mass Spectrometry in Polyunsaturated Fatty Acid and Sphingolipid Measurements

Mutay ASLAN ( Turkey )

11:30 – 12:00

Toxicological Properties of Metal-based Nanoparticles: What makes the difference?

Andrea HARTWIG (Germany)

Lipidomic Research in Toxicology

Suna SABUNCUOGLU (Turkey)

12:00 – 12:30
CLOSING CEREMONY